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Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
Drugs in...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...

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Updated: May 14, 2026

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
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Published on: February 3, 2026

Emergency contraception.

P G L Lalitkumar1, Cecilia Berger, Kristina Gemzell-Danielsson

  • 1Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet/WHO-Collaborating Center, Karolinska University Hospital, Stockholm, Sweden.

Best Practice & Research. Clinical Endocrinology & Metabolism
|February 7, 2013
PubMed
Summary

Emergency contraception (EC) options include copper intrauterine devices (IUDs) and hormonal pills. Ulipristal acetate (UPA) pills are most effective, but research is needed for specific populations and long-term use.

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Area of Science:

  • Reproductive Health
  • Pharmacology

Background:

  • Emergency contraception (EC) is crucial for preventing unintended pregnancies.
  • Various methods exist, each with distinct efficacy and mechanisms.

Purpose of the Study:

  • To review available EC methods, focusing on efficacy, side effects, and mechanisms.
  • To identify knowledge gaps and areas for future research in EC.

Main Methods:

  • Literature review of emergency contraception methods.
  • Analysis of efficacy, side effects, and mechanisms of action for different EC options.

Main Results:

  • Copper intrauterine devices (IUDs) are the most effective EC method and can be used for ongoing contraception.
  • Ulipristal acetate (UPA) is the most effective hormonal EC pill, likely due to superior follicular rupture prevention.
  • Levonorgestrel 1.5 mg is a widely used hormonal EC pill.

Conclusions:

  • Further research is needed to optimize EC for lactating and obese women.
  • Investigating UPA interactions with regular contraception and "bridging" strategies is essential.
  • Future EC efficacy improvements may come from methods targeting the endometrium.