Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...

Bacterial Gastroenteritis

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

Cholera

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

Inflammatory Bowel Disease I: Introduction

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hypertransaminasemia Is a Marker of Severity in Children Hospitalized for Influenza.

Influenza and other respiratory viruses·2026

Same author

Impact of regional heterogeneity of RSV infection prophylaxis on bronchiolitis in Italy.

Italian journal of pediatrics·2026

Same author

Clinical Features and Predictors of Severity in Children Hospitalized With Human Metapneumovirus: A Multicenter Italian Study.

The Pediatric infectious disease journal·2026

Same author

Appropriateness and Abuse of Antipyretics, Anti-Inflammatory Drugs and Antibiotics in Children and Adults.

Antibiotics (Basel, Switzerland)·2026

Same author

Inter-society consensus on the management of acute bloody diarrhea and shiga toxin-producing Escherichia coli infection in the molecular microbiology era.

Italian journal of pediatrics·2026

Same author

Phenotyping Pediatric Long COVID: Symptom Clusters from a Longitudinal Multicenter Italian Cohort.

Children (Basel, Switzerland)·2026

Search research articles

Related Experiment Video

Updated: May 14, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

Chronic diarrhoea in children.

Alfredo Guarino¹, Andrea Lo Vecchio, Roberto Berni Canani

¹Department of Pediatrics, University of Naples Federico II, Via S. Pansini 5, Naples, Italy. alfguari@unina.it

Best Practice & Research. Clinical Gastroenterology

|February 7, 2013

Summary

This summary is machine-generated.

Chronic diarrhoea in children presents a diverse range of causes and requires age-specific management. Diagnosis and treatment strategies differ significantly from adults, emphasizing noninvasive methods and nutritional interventions.

More Related Videos

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Chronic Salmonella Infection Induced Intestinal Fibrosis

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Related Experiment Videos

Last Updated: May 14, 2026

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

Published on: December 27, 2024

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Chronic Salmonella Infection Induced Intestinal Fibrosis

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Area of Science:

Pediatrics
Gastroenterology

Background:

Chronic diarrhoea in children exhibits an age-related spectrum of causes.
Common causes include persistent infections, nutrient intolerances (e.g., cow's milk protein), toddler's diarrhoea, coeliac disease, and increasing rates of inflammatory bowel diseases in older children.

Purpose of the Study:

To outline the age-specific diagnostic and management approaches for chronic diarrhoea in children.
To highlight the distinct differences in paediatric chronic diarrhoea compared to adult cases.

Main Methods:

Diagnosis relies on noninvasive techniques, with endoscopy guided by clinical criteria and noninvasive test results.
A stepwise diagnostic approach is recommended to potentially reduce the need for endoscopy.
Assessment includes evaluating digestive absorptive functions and intestinal inflammation.

Main Results:

Chronic diarrhoea in children is complex and age-dependent.
Management strategies, particularly nutritional interventions, differ substantially from adult protocols.
Noninvasive diagnostic methods and a stepwise approach can optimize the diagnostic yield and reduce invasive procedures.

Conclusions:

Chronic diarrhoea in children is a distinct clinical entity requiring specialized, age-appropriate management.
The diagnostic and therapeutic strategies must be tailored to the specific age group and underlying aetiology.
Effective management emphasizes noninvasive diagnostics and nutritional support, diverging significantly from adult care paradigms.