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Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Reticular Dermis

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Related Experiment Video

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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[Dermatology for general physicians].

¹Dermatologie, Universitätsspital Basel. haslersa@uhbs.ch

|February 7, 2013

Summary

This summary is machine-generated.

General practitioners require dermatology knowledge as 20% of the population has skin conditions. Common issues include eczema, infections, and benign tumors, often treated with antihistamines, antimicrobials, and topical steroids.

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Area of Science:

Dermatology
General Practice
Internal Medicine

Context:

Skin conditions affect 20% of the population.
Patients frequently self-medicate or consult general practitioners (GPs) for dermatologic issues.
GPs manage common skin problems like eczema, infections, and benign tumors.

Purpose:

To highlight the importance of dermatologic knowledge for general practitioners.
To outline common skin conditions encountered in primary care.
To identify frequently prescribed dermatologic medications.

Summary:

Eczema, skin infections, and benign skin tumors are prevalent conditions seen by GPs.
Antihistamines, antimicrobial agents, and topical steroids are commonly prescribed for skin diseases.
The skin acts as a barrier, and skin lesions can indicate internal organ disorders.

Impact:

Enhancing GP dermatology skills can improve patient outcomes for common skin diseases.
Recognizing skin manifestations of internal diseases can aid in early diagnosis.
This knowledge bridges primary care and specialized dermatology, improving patient management.