Polymorphisms in DNA repair genes and susceptibility to glioma in a chinese population

Wei-Ran Pan1, Gang Li, Jun-Hong Guan

  • 1Department of Neurosurgery, Shengjing Affiliated Hospital of China Medical University, Shenyang 110004, China. panweiran5432@126.com.

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Loss of Tumor Suppressor Gene Functions

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Mismatch Repair01:20

Mismatch Repair

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DNA Distortion and Damage
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