Related Experiment Video
Updated: May 14, 2026

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface
Published on: December 30, 2025
Testing for HIV during pregnancy: 5 years after changing German pregnancy guidelines
Franziska Pauly1, Anne-Lena Freese, Michaela Golic
1Department of Obstetrics, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Objective:
A known HIV status is the most important step in preventing mother-to-child transmission of HIV and screening for HIV is recommended by German prenatal guidelines. In our study, we wanted to ascertain the prevalence of HIV-testing in a pregnant inner-city cohort.
Methods:
Prenatal records of 279 women were prospectively studied, and the testing confirmed with the prenatal care providers.
Results:
82.4 % of the patients had been tested for HIV during pregnancy. The test was refused by 4.0 % of the women. Contrary to current guidelines, in more than half of the cases documentation of the test or the result was found in the women's prenatal care papers.
Conclusions:
Even though a large majority of pregnant women are screened for HIV, the rates of testing need to be increased. Education of patients and providers as well as changing to the "opt-out" approach used in other countries may prevent unnecessary mother-to-child transmission of HIV.
Related Concept Videos
Sexually Transmitted Infections
Teratogenicity
