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Related Experiment Video

Updated: May 14, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Sepsis and maternal mortality.

Colleen D Acosta1, Marian Knight

  • 1National Perinatal Epidemiology Unit, University of Oxford, UK. colleen.acosta@npeu.ox.ac.uk

Current Opinion in Obstetrics & Gynecology
|February 7, 2013
PubMed
Summary
This summary is machine-generated.

Maternal deaths from sepsis are underestimated due to reporting issues. Addressing risk factors and improving sepsis recognition are crucial for effective interventions globally.

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Last Updated: May 14, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

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Published on: June 15, 2019

A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • Sepsis is a significant, preventable cause of maternal mortality worldwide.
  • Despite global efforts, reducing maternal deaths from sepsis remains a challenge.

Purpose of the Study:

  • To review measurement challenges, trends, causes, and interventions for maternal sepsis deaths.
  • To compare sepsis-related maternal mortality in high-income and low-income countries.

Main Methods:

  • Literature review focusing on sepsis in maternal mortality.
  • Analysis of reporting data, risk factors, and management strategies.

Main Results:

  • Maternal deaths from sepsis are significantly underestimated due to under-reporting and misclassification.
  • Increased invasive group A streptococcal infections contribute to recent sepsis deaths in some high-income countries.
  • Failure to recognize infection severity is a universal risk factor; outcomes vary with intensive care resources.

Conclusions:

  • Robust data collection and analysis are essential for understanding sepsis risk factors and pathways.
  • Effective treatment strategies must consider resource availability and causal pathways.