Related Experiment Video
Updated: May 14, 2026
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
Transcranial magnetic stimulation as an efficient treatment for psychogenic movement disorders
Béatrice Garcin1, Emmanuel Roze, Francine Mesrati
1Département de Neurologie, Hôpital Pitié-Salpêtrière, Centre de Référence Maladie de Parkinson, APHP, Paris, France.
Background:
Management of psychogenic movement disorders (PMDs) is challenging for neurologists and, to date, there is no consensus about their treatment. Recent studies suggested a possible therapeutic effect of repeated transcranial magnetic stimulation (TMS) in psychogenic paralysis and tremor.
Objective:
To document the clinical impact of TMS in PMDs.
Methods:
We blindly video scored symptoms of consecutive patients with PMD who were recorded before and after TMS. TMS was delivered at low frequency (0.25 Hz) over the motor cortex contralateral to symptoms.
Results:
Twenty-four patients were included. They presented with dystonia, myoclonus, tremor, Parkinsonism or stereotypies. The median duration of symptoms before TMS was 2.8 years (6 months to 30 years). The overall score of 75% of patients improved by >50% and, furthermore, the clinical benefits were sustained upon protracted follow-up (median 19.8 months). There was no correlation between improvement and duration of symptoms before TMS.
Conclusions:
TMS is a therapeutic option for PMDs, including chronic PMDs.
