[Case report - pediatric visceral leishmaniasis]
Related Experiment Video
Updated: May 14, 2026

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
Jan Pavelka1, Lenka Krbková, Eliška Zárošská
1Clinic of Pediatric Infectious Diseases, The University Hospital Brno, Czech Republic. pavelkajan@seznam.cz
Abstract:
The diagnosis of visceral leishmaniasis (VL) is not an easy task. The clinical presentation of VL is similar to lymphomas which have significantly higher incidence in our country. This fact is one of the complications in the diagnosis of VL. Moreover, diagnostic methods have low sensitivity and bone marrow aspiration is necessary. We present a case report of a patient who fell ill in the first year of life and due to atypical lifestyle of his parents was seriously examined after 11 months from the first symptoms of the disease. Many problems with the diagnostic algorithm leading to the definitive diagnosis of VL were encountered. Thereafter, the patient underwent treatment with amphotericin B lipid complex. The course was complicated by febrile neutropenia and anemia, with the necessity for blood transfusion.

