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Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Viral Meningitis01:18

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Arboviral Encephalitis

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Related Experiment Video

Updated: May 14, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

Neonatal varicella: A case report.

Ak Bhardwaj1, Pd Sharma, A Sharma

  • 1Professor, Department of Pediatrics, MM Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India.

The Australasian Medical Journal
|February 7, 2013
PubMed
Summary
This summary is machine-generated.

Neonatal varicella (chicken pox) can occur if a mother has active skin lesions during delivery. Prompt antiviral therapy in newborns with chicken pox leads to uneventful recovery.

Keywords:
Neonatal varicellacongenital chickenpoxpregnancy

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Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neonatology

Background:

  • Chicken pox (varicella) is a common childhood illness, typically mild.
  • Neonates usually have passive immunity from their mothers, making chicken pox rare in this age group.
  • Characteristic varicella lesions are vesicular with an erythematous base and pruritus, usually sparing palms and soles.

Observation:

  • A case of neonatal varicella is presented.
  • The neonate contracted varicella during the perinatal period from the mother who had active skin eruptions at delivery.
  • Clinical disease manifested on the fifth day of life.

Findings:

  • Neonatal varicella occurred despite expected passive immunity.
  • Early diagnosis and intervention were crucial.
  • Specific antiviral therapy was administered to both mother and neonate.

Implications:

  • This case highlights the importance of recognizing neonatal varicella.
  • Maternal varicella during delivery poses a risk to newborns.
  • Timely antiviral treatment is effective in managing neonatal varicella, ensuring a positive outcome.