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Updated: May 14, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
[Application of peripherally inserted central catheter for parenteral nutrition in critically ill neonates]
Meng-Lin Tang1, Ji-Ping Li, Yan Liao
1Pediatric Intensive Care Unit, West China Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To apply peripherally inserted central catheter (PICC) in critically ill neonates who require long-term parenteral nutrition.
Methods:
A retrospective review of 98 critically ill neonates who had a PICC inserted and received long-term parenteral nutrition from March to December 2011 was performed.
Results:
The PICC insertion succeeded in 74.5% (73/98) of the cases at the first attempt. The catheter remained for an average of (19.7 +/- 2.0) days. Of the 98 cases, 92 underwent planned extubation after enteral nutrition was fully established; 10 developed complications within the follow-up period of 956 days. The PICC-associated complications occurred at a rate of 10. 5 per 1000 catheter-days, including infection (n=0), phlebitis (n=1), accidental dislodgement (n=3), catheter occlusion (n=3), and hemorrhage in puncture point (n=3).
Conclusion:
PICC can be used as a safe venous access for critically ill neonates for long-term parenteral nutrition. PICC-associated complications can be reduced through improving nursing skills, especially for catheter-related infection.
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