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Contact dermatitis in patients with leg ulcers
G Angelini1, F Rantuccio, C L Meneghini
1Department of Dermatology of the University, Bari, Italy.
Contact Dermatitis
|January 1, 1975
Summary
Contact allergy to topical preparations is common in stasis dermatitis patients. Identifying allergens like neomycin, parabens, and lanolins is crucial for preventing chronic allergic contact dermatitis.
Area of Science:
- Dermatology
- Allergology
Background:
- Stasis dermatitis often involves topical treatments.
- Contact allergy to topical agents can complicate stasis dermatitis management.
Purpose of the Study:
- To determine the incidence of contact allergy to common topical preparation ingredients in stasis dermatitis patients.
- To identify specific allergens causing contact dermatitis in this patient group.
Main Methods:
- Patch testing was performed on 306 patients with stasis dermatitis.
- Patients were tested with 63 substances, including active principles and excipients.
Main Results:
- 177 out of 306 patients (57.8%) showed positive reactions to at least one tested substance.
- Common allergens included neomycin, sulfonamide, promethazine, parabens, lanolins, and benzoyl peroxide.
- Substances from the 'para' group, benzocaine, and aniline derivatives were frequent sensitizers, often indicating cross-reactivity.
Conclusions:
- Contact allergy is a significant issue in stasis dermatitis.
- Identifying specific allergens is essential to prevent dermatitis chronicity and spread.
- Restricting topical applications to non-allergenic substances is recommended.
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