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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

Hepatitis C virus in pregnancy.

Mona R Prasad¹, Jonathan R Honegger

¹Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Wexner Medical Center, The Ohio State University College of Medicine, Columbus, OH 43210, USA. mona.prasad@osumc.edu

American Journal of Perinatology

|February 8, 2013

Summary

Hepatitis C virus (HCV) in pregnancy is understudied, with a 2-8% risk of mother-to-child transmission (MTCT). Understanding HCV MTCT mechanisms is crucial for developing prevention strategies.

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A Protocol for Analyzing Hepatitis C Virus Replication

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Area of Science:

Hepatology
Infectious Diseases
Maternal-Fetal Medicine

Background:

Hepatitis C virus (HCV) remains a significant global health concern.
Despite advances, HCV in pregnancy is a neglected area.
Pregnant women with HCV face risks including infant transmission and adverse pregnancy outcomes.

Purpose of the Study:

To highlight the neglected aspect of Hepatitis C virus (HCV) in pregnancy.
To underscore the importance of understanding HCV mother-to-child transmission (MTCT) mechanisms and timing.
To emphasize the need for developing effective prevention strategies for HCV vertical transmission.

Main Methods:

Literature review and synthesis of existing research on HCV in pregnancy.
Analysis of known risk factors for HCV MTCT.
Comparison of HCV MTCT with other viral infections like HIV.

Main Results:

HCV-monoinfected pregnant women have a 2-8% risk of transmitting the virus to their infants.
The precise mechanisms and timing of HCV MTCT are not fully understood.
Effective methods for preventing HCV vertical transmission are currently lacking.

Conclusions:

Further research into HCV pathogenesis and MTCT during pregnancy is essential.
Understanding these processes can guide the development of novel prevention strategies.
This knowledge is particularly relevant with the emergence of interferon-free treatment options for HCV.