Five clinical cases of Necropsobacter rosorum bacteremia

Thean Yen Tan1, Lily Siew Yong Ng, Li Ching Eng

  • 1Department of Laboratory Medicine, Changi General Hospital, Singapore. thean_yen_tan@cgh.com.sg

Insights

Necropsobacter rosorum bacteremia, often from pelvic infections, is frequently misidentified by commercial systems. This misidentification may hinder its recognition as a significant human pathogen, impacting patient care.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Bacteremia is a serious condition requiring accurate pathogen identification for effective treatment.
  • Necropsobacter rosorum is a bacterium that has been rarely reported in human infections.
  • Accurate identification of microorganisms is crucial for clinical decision-making and patient outcomes.

Observation:

  • This study describes five cases of bacteremia caused by Necropsobacter rosorum.
  • The infections originated from intra-abdominal or localized soft tissue infections in the pelvic region.
  • Clinical presentations included serious infections requiring medical intervention.

Findings:

  • Necropsobacter rosorum was consistently misidentified by commonly used commercial identification systems.
  • The misidentification by diagnostic systems may lead to delayed or incorrect diagnosis.
  • This highlights a potential gap in the current microbiological diagnostic capabilities for this organism.

Implications:

  • Delayed recognition of Necropsobacter rosorum as a pathogen can impact patient management and treatment strategies.
  • There is a need to improve identification methods for Necropsobacter rosorum in clinical laboratories.
  • Enhanced awareness and diagnostic accuracy are essential for addressing Necropsobacter rosorum-associated infections.

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Bacterial Phylum Bacteroidota01:26

Bacterial Phylum Bacteroidota

The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...