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Synthesis of 6'-deoxy-6'-fluorosucrose
Vikram Gaddam1, Michael Harmata
1Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211, United States.
Abstract:
A facile synthesis of 6'-deoxy-6'-fluorosucrose has been developed. The title compound is available in six linear steps in 44% overall yield from commercially available sucrose. The synthesis involves rapid and convenient fluorination and deprotection conditions. This procedure would be very useful for the incorporation of radioactive [(18)F].
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