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Minimizing complications associated with percutaneous central venous catheter placement in children: recent advances
John M Costello1, Timothy C Clapper, David Wypij
1Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA. jmcostello@luriechildrens.org
Insights
Complications from central venous catheters in critically ill children are common. Strategies like ultrasound guidance and infection bundles are improving outcomes, though more research is needed for thrombosis prevention.
Area of Science:
- Pediatric Critical Care Medicine
- Vascular Access Devices
- Medical Device Complications
Background:
- Central venous catheters are vital in pediatric critical care but associated with significant complications.
- Understanding the prevalence and nature of these complications is crucial for patient safety.
- Existing knowledge on complication rates and prevention strategies requires synthesis.
Purpose of the Study:
- To summarize current knowledge on central venous catheter complications in critically ill children.
- To review and highlight evolving strategies for minimizing these complications.
- To identify areas where further research is needed.
Main Methods:
- Comprehensive literature review of PubMed and EBSCOhost databases.
- Keywords included: central venous catheter, children, ultrasound, infection, thrombosis, thromboembolism.
- Focus on pediatric literature, prioritizing randomized clinical trials and prospective studies.
Main Results:
- Complications are frequent in pediatric central venous catheter placement, potentially linked to vascular anatomy.
- Thrombosis is an emerging concern with limited evidence-based preventive measures.
- Catheter-associated bloodstream infection rates have declined due to enhanced education and care bundles.
Conclusions:
- Central venous catheter complications in children are prevalent and multifactorial.
- Improved infection control measures have successfully reduced bloodstream infections.
- Ultrasound guidance shows promise for catheter placement, but further investigation is warranted, especially for thrombosis.
- Evidence-based strategies for preventing thrombosis require development.
Objectives:
To summarize existing knowledge regarding the prevalence of complications associated with temporary percutaneous central venous catheters placed in critically ill children, and to review evolving strategies to minimize the prevalence of these complications.
Data Sources:
Literature review was performed: PubMed and EBSCOhost were searched using the terms central venous catheter, children, ultrasound, infection, thrombosis, and thromboembolism in various combinations. Citations of interest from identified articles were also reviewed.
Study Selection:
The review focused primarily on pediatric literature relevant to the topic of interest.
Data Extraction And Synthesis:
Randomized clinical trials and other prospective studies were discussed in greater detail than retrospective, single-center investigations.
Conclusions:
Complications during percutaneous central venous catheter placement in children are not rare and may be in part attributable to abnormalities in vascular anatomy. Thromboses in children with central venous catheters are increasingly recognized as an important problem for which evidence-based preventive measures are lacking. Catheter-associated bloodstream infection rates in critically ill children have markedly decreased over the last decade, associated with an increased emphasis on staff education and the use of insertion and maintenance bundles. Available evidence tends to support the use of two-dimensional ultrasound to augment the landmark technique for catheter placement, but more studies are needed.
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