Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early referral of patients with suspected polymyalgia rheumatica - A systematic review.

Seminars in arthritis and rheumatism·2023
Same author

Association of ultrasound-confirmed axillary artery vasculitis and clinical outcomes in giant cell arteritis.

Seminars in arthritis and rheumatism·2022
Same author

A study on echocardiographic findings in hospitalized patients with connective tissue diseases.

Scandinavian journal of rheumatology·2021
Same author

[S2k guidelines: management of large-vessel vasculitis].

Zeitschrift fur Rheumatologie·2020
Same author

[S2k guidelines (executive summary): management of large-vessel vasculitis].

Zeitschrift fur Rheumatologie·2020
Same author

[Imaging diagnostics in large vessel vasculitis].

Zeitschrift fur Rheumatologie·2019
Same journal

[Prevention strategies in rheumatoid arthritis : From primary prevention to targeted drug interception].

Zeitschrift fur Rheumatologie·2026
Same journal

Methodological concerns and data discrepancies in the indirect treatment comparison of belimumab and anifrolumab.

Zeitschrift fur Rheumatologie·2026
Same journal

Evaluating the comparative efficacy of belimumab vs. anifrolumab in systemic lupus erythematosus: a response.

Zeitschrift fur Rheumatologie·2026
Same journal

[Update: DMARDs for MGUS].

Zeitschrift fur Rheumatologie·2026
Same journal

[A potpourri of diagnoses-Unusual manifestations of a chronic inflammatory bowel disease : Case report].

Zeitschrift fur Rheumatologie·2026
Same journal

[Not measurable but immeasurably important : Fever-The leading symptom of ancient medical theory].

Zeitschrift fur Rheumatologie·2026
See all related articles

Related Experiment Videos

[Polymyalgia rheumatica].

W A Schmidt1

  • 1Rheumaklinik Berlin - Buch, Immanuel Krankenhaus Berlin, Lindenberger Weg 19, 13125, Berlin. w.schmidt@immanuel.de

Zeitschrift Fur Rheumatologie
|February 9, 2013
PubMed
Summary
This summary is machine-generated.

Polymyalgia rheumatica (PMR) causes pain and stiffness, primarily in older adults. Glucocorticoid treatment is effective, with most patients improving within two years.

Related Experiment Videos

Area of Science:

  • Rheumatology
  • Internal Medicine
  • Immunology

Context:

  • Polymyalgia rheumatica (PMR) is a common inflammatory condition affecting individuals over 50.
  • PMR presents with bilateral shoulder and pelvic girdle pain, malaise, morning stiffness, and weight loss.
  • Elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels are characteristic of PMR.

Purpose:

  • To describe the clinical characteristics, diagnostic findings, and treatment of polymyalgia rheumatica.
  • To highlight the typical patient demographic and epidemiological features of PMR.
  • To outline the management strategies and prognosis for patients with polymyalgia rheumatica.

Summary:

  • PMR typically affects women over 50, presenting with symmetrical proximal muscle pain and stiffness.
  • Diagnostic tools include clinical symptoms, elevated inflammatory markers (ESR, CRP), and imaging (ultrasound, MRI, PET) showing inflammation.
  • Rapid symptom improvement with glucocorticoids is a hallmark of PMR, with treatment usually lasting around two years.

Impact:

  • Early diagnosis and appropriate glucocorticoid therapy lead to significant symptom relief and improved quality of life for PMR patients.
  • Understanding PMR's association with giant cell arteritis is crucial for timely diagnosis and prevention of vision loss.
  • This information aids clinicians in managing PMR effectively, optimizing treatment duration, and minimizing potential side effects.