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Related Experiment Video

Updated: May 14, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

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Transcranial direct current stimulation improves swallowing function in stroke patients.

Takashi Shigematsu1, Ichiro Fujishima, Kikuo Ohno

  • 1Department of Rehabilitation Medicine, Hamamatsu City Rehabilitation Hospital, Shizuoka, Japan. shige1206jp@gmail.com

Neurorehabilitation and Neural Repair
|February 9, 2013
PubMed
Summary

Noninvasive brain stimulation using anodal transcranial direct current stimulation (tDCS) combined with swallowing therapy significantly improved post-stroke dysphagia. This treatment offers a promising approach for enhancing swallowing function and reducing complications.

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Clinical Neurology

Background:

  • Post-stroke dysphagia is a persistent condition with significant complications.
  • Effective treatments for post-stroke dysphagia are crucial for patient recovery and quality of life.

Purpose of the Study:

  • To evaluate the efficacy of noninvasive brain stimulation targeting the pharyngeal motor cortex combined with intensive swallowing therapy.
  • To determine if this combined approach can improve swallowing function in patients with post-stroke dysphagia.

Main Methods:

  • A randomized controlled trial involving 20 patients with post-stroke dysphagia.
  • Intervention group received anodal transcranial direct current stimulation (tDCS) (1-mA) for 20 minutes per session, 10 sessions total, alongside conventional swallowing therapies.
  • Control group received sham tDCS with simultaneous conventional swallowing therapies.
  • Swallowing function was assessed using the Dysphagia Outcome and Severity Scale (DOSS) before, immediately after, and 1 month post-intervention.

Main Results:

  • The anodal tDCS group showed significant improvements in DOSS scores immediately after treatment (1.4 points, P = .006) and at 1-month follow-up (2.8 points, P = .004).
  • The sham tDCS group demonstrated smaller improvements (0.5 points immediately, P = .059; 1.2 points at 1 month, P = .026).
  • Improvements in the anodal tDCS group were significantly greater than in the sham group (P = .029 immediately; P = .007 at 1 month).

Conclusions:

  • Anodal tDCS applied to the ipsilesional pharyngeal motor cortex, when combined with peripheral sensorimotor activities, significantly enhances swallowing function.
  • This noninvasive brain stimulation technique represents a promising therapeutic strategy for managing post-stroke dysphagia.