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Diabetic somatic neuropathy.
Zdravko A Kamenov1, Latchezar D Traykov
1University Hospital Alexandrovska, Medical University - Sofia, Sofia, Bulgaria. zkamenov@hotmail.com
Advances in Experimental Medicine and Biology
|February 9, 2013
Summary
Diabetic neuropathy (DN) is a common, complex complication affecting the whole body. Tight glycemic control is key for prevention, while symptomatic treatments help manage painful diabetic neuropathy.
Area of Science:
- Diabetology
- Neurology
- Vascular Complications
Background:
- Diabetic neuropathy (DN) is a prevalent and challenging complication of diabetes.
- It impacts the entire body with varied clinical presentations, notably leading to diabetic foot, ulceration, and amputation.
- DN is often overlooked and difficult to treat compared to other diabetic vascular issues.
Purpose of the Study:
- To discuss the definition, epidemiology, pathophysiology, and classification of somatic DN.
- To explore practical aspects, clinical presentations, diagnostic methods, and treatment options for somatic DN.
- To highlight gender differences in DN, which are rarely discussed.
Main Methods:
- Review of existing literature on diabetic neuropathy.
- Discussion of clinical presentation and diagnostic approaches for different types of somatic DN.
- Exploration of current and potential treatment strategies.
Main Results:
- Somatic and autonomic DN can lead to severe outcomes like diabetic foot and amputation.
- Despite available testing devices, DN is under-researched and treatment is complicated by complex pathogenetic mechanisms.
- Tight glycemic control is the primary method for preventing or slowing DN progression.
Conclusions:
- Diabetic neuropathy remains a significant challenge in diabetes management.
- Effective management requires a multi-faceted approach including glycemic control and symptomatic treatment.
- Further research into novel treatment options for DN is essential.
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