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Updated: May 14, 2026
A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
[Fractional exhaled nitric oxide measurement during specific inhalation challenge tests]
Gianni Pala1, Patrizia Pignatti, Marco Caminati
1Servizio Autonomo di Allergologia e Immunologia Clinica, Fondazione Salvatore Maugeri, IRCCS, Istituto Scientifico di Pavia, Via Maugeri 10, 27100 Pavia, Italia. giannipalass@libero.it
Abstract:
The aim of the work is to evaluate the usefulness of the evaluation of the fractional exhaled nitric oxide (FeNO) in patients with suspected occupational asthma (OA) during the specific inhalation challenge (SIC). We evaluated 5 subjects with OA confirmed by SIC and 7 subjects with negative SIC result. In subjects with confirmed OA, but not in SIC negative subjects, a significant increase in FeNO values has been reported. In conclusion, FeNO measurement may be considered a useful tollfor the evaluation of bronchial inflammation during the SIC.
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