Related Experiment Video
Updated: May 14, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Recent developments on domino metathesis reactions in India
Rahul S Nandurdikar1, Krishna P Kaliappan
1Department of Chemistry Indian Institute of Technology Bombay Powai, Mumbai, India.
Indian researchers extensively utilize domino metathesis reactions with ruthenium-carbene complexes. This powerful synthetic strategy enables the efficient construction of intricate polycyclic systems and complex molecular architectures.
Area of Science:
- Organic Chemistry
- Catalysis
- Synthetic Chemistry
Background:
- Domino metathesis reactions offer efficient pathways to complex molecules.
- Ruthenium-carbene complexes are versatile catalysts for these transformations.
- Research in India has focused on applying these reactions in synthesis.
Purpose of the Study:
- To review the advancements in domino metathesis reactions in India.
- To highlight the use of ruthenium-carbene complexes in these reactions.
- To showcase the synthesis of polycyclic systems and complex molecular architectures.
Main Methods:
- Review of published research on domino metathesis in India.
- Focus on studies employing ruthenium-carbene catalysts.
- Analysis of synthetic strategies for polycyclic and complex molecules.
Main Results:
- Domino metathesis with ruthenium-carbene complexes is a key tool for Indian synthetic chemists.
- This methodology facilitates the construction of diverse polycyclic frameworks.
- Complex molecular architectures are efficiently accessed through these reactions.
Conclusions:
- Ruthenium-carbene catalyzed domino metathesis is a significant area of research in India.
- The reaction enables streamlined synthesis of valuable chemical structures.
- Continued exploration promises further advancements in molecular synthesis.
Related Concept Videos
Olefin Metathesis Polymerization: Overview
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)
Cycloaddition Reactions: MO Requirements for Thermal Activation
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
