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Functional imaging of the liver.

Vicky Goh¹, Sofia Gourtsoyianni, Dow-Mu Koh

¹Division of Imaging Sciences and Biomedical Engineering, King's College London, London, UK. Vicky.goh@kcl.ac.uk

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Summary

Functional imaging offers a novel approach to liver disease assessment by detecting pathophysiologic changes earlier than traditional anatomical imaging. This review explores advanced MRI, CT, and ultrasound techniques for improved liver evaluation.

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Area of Science:

Radiology
Medical Imaging
Hepatology

Background:

Anatomical imaging is standard for liver evaluation but detects structural changes late.
Functional imaging complements anatomical methods by assessing pathophysiologic alterations.
Growing interest exists in functional imaging for clinical and research liver disease assessment.

Purpose of the Study:

To review common functional imaging techniques for liver applications.
To highlight the potential of functional imaging in addressing diagnostic challenges.
To discuss the application of functional MRI, CT, and ultrasound in liver disease.

Main Methods:

Review of functional magnetic resonance imaging (fMRI) techniques for the liver.
Review of functional computed tomography (fCT) techniques for the liver.
Review of functional ultrasound imaging techniques for the liver.

Main Results:

Functional imaging allows for earlier detection of liver disease compared to anatomical imaging.
Quantification of pathophysiologic alterations is achievable with functional techniques.
Functional imaging aids in solving diagnostic dilemmas not resolvable by conventional methods.

Conclusions:

Functional imaging techniques show significant promise for liver disease evaluation.
Integrating functional imaging can enhance diagnostic accuracy and patient management.
Further research and clinical application of these techniques are warranted.