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Updated: May 14, 2026

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
Published on: June 7, 2024
Positron emission tomography-computed tomography in liver imaging.
Bhuey Sharma1, Axel Martin, Imene Zerizer
1Department of Imaging, Royal Marsden Hospital, London, UK. Bhuey.Sharma@rmh.nhs.uk
Positron emission tomography (PET) offers advanced liver imaging for detecting and characterizing liver lesions. This functional imaging technique aids in patient management, prognostication, and assessing treatment response in liver cancer.
Area of Science:
- Oncological Imaging
- Nuclear Medicine
- Hepatobiliary Medicine
Background:
- Positron emission tomography (PET) is an evolving imaging modality integrating anatomical and functional information.
- Its application in oncological imaging, particularly for the liver, is expanding.
- Accurate liver lesion detection and characterization are crucial for patient management.
Purpose of the Study:
- To review the utility of PET imaging in liver cancer management.
- To discuss PET's role in lesion detection, characterization, and prognostication.
- To highlight PET's application in pre-transplant evaluation and treatment response assessment.
Main Methods:
- Systematic review of current literature on PET imaging in liver oncology.
- Analysis of PET's performance in detecting and characterizing primary and metastatic liver lesions.
- Evaluation of functional PET imaging's role in prognostication and treatment monitoring.
Main Results:
- PET demonstrates significant value in detecting and characterizing various liver malignancies, including hepatocellular carcinoma and cholangiocarcinoma.
- It is effective in assessing metastatic disease from colorectal cancer and other primary sites.
- Functional PET imaging aids in prognostication, pre-liver transplant assessment, and response evaluation post-therapy.
Conclusions:
- PET imaging is a valuable tool for optimizing clinical management of liver cancer patients.
- Its functional insights enhance diagnostic accuracy and therapeutic decision-making.
- Emerging PET biomarkers promise further advancements in liver oncology.
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