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Published on: December 5, 2013
Human serum albumin (HSA) nanoparticles stabilized with intermolecular disulfide bonds
Wentan Wang1, Yanbin Huang, Shufang Zhao
1Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.
Chemical Communications (Cambridge, England)
|February 12, 2013
Abstract:
We have presented a self-cross-link strategy to fabricate HSA nanoparticles using a desolvation method. The nanoparticles were stabilized by intermolecular disulfide bonds while still dissolvable in reducing media. The fabrication process does not involve any toxic chemicals and hence the nanoparticles may be useful as a drug carrier.
