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Related Concept Videos

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
Mass Analyzers: Overview01:13

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
Electrospray Ionization (ESI) Mass Spectrometry01:12

Electrospray Ionization (ESI) Mass Spectrometry

Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then passed on to...
Mass Spectrometers01:16

Mass Spectrometers

This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
Mass Spectrum: Interpretation01:24

Mass Spectrum: Interpretation

An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a soft-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.To...

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Related Experiment Video

Updated: May 14, 2026

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps
11:45

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

Published on: August 17, 2017

A simulation study of the planar electrostatic ion trap mass analyzer.

Li Ding1, Ranjan Badheka, Zhengtao Ding

  • 1Shimadzu Research Laboratory (Europe) Ltd., Manchester, UK. li.ding@srlab.co.uk

Journal of the American Society for Mass Spectrometry
|February 12, 2013
PubMed
Summary

A new planar electrostatic ion trap design offers greater space charge tolerance and achieves 80,000 FWHM mass resolution. This advanced ion trap technology optimizes ion motion for high-precision mass spectrometry.

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T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis
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T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Published on: July 31, 2010

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Last Updated: May 14, 2026

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps
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T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis
16:40

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Published on: July 31, 2010

Area of Science:

  • Physics
  • Analytical Chemistry
  • Instrument Design

Background:

  • Linear electrostatic ion traps have limitations in trapping space and space charge tolerance.
  • Improving ion trapping efficiency and mass resolution is crucial for advanced analytical techniques.

Purpose of the Study:

  • To develop a planar electrostatic ion trap with enhanced trapping capacity and space charge tolerance.
  • To optimize the trap design for isochronous ion motion and high mass resolution.

Main Methods:

  • Simulated ion oscillatory motions within a rotationally symmetrical electrode configuration.
  • Optimized electric field distribution for isochronous motion across R, z, and φ directions.
  • Utilized Fast Fourier Transform (FFT) on image charge signals from multiple electrodes for mass analysis.

Main Results:

  • Achieved isochronous ion motion, mitigating energy spread effects.
  • Demonstrated a mass resolution of 80,000 FWHM.
  • Successfully eliminated unwanted harmonic peaks in FFT spectra through signal linear combination.

Conclusions:

  • The planar electrostatic ion trap design significantly expands trapping space and improves space charge tolerance.
  • The optimized trap design enables high-precision mass measurements with exceptional resolution.
  • This technology offers a promising advancement for mass spectrometry applications.