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About a bloodstream Corynebacterium striatum isolate.

Vincenzo Savini1, Giovanni Gherardi, Marco Favaro

  • 1Clinical Microbiology and Virology, Spirito Santo Hospital, via Fonte Romana 8, CAP 65124, Pescara (PE), Italy, vincenzo_savini@libero.it.

Folia Microbiologica
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PubMed
Summary
This summary is machine-generated.

Corynebacterium striatum, usually a skin bacteria, can cause serious bloodstream infections. Monitoring its antibiotic resistance is crucial for effective treatment of these nosocomial infections.

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Area of Science:

  • Clinical microbiology
  • Infectious diseases
  • Antimicrobial resistance

Background:

  • Corynebacterium striatum is frequently misidentified as a contaminant in blood cultures due to its skin saprophyte nature.
  • However, C. striatum can cause genuine bloodstream infections (bacteremias).
  • The increasing prevalence of multidrug-resistant strains in hospital-acquired infections is a significant concern.

Purpose of the Study:

  • To highlight the clinical significance of Corynebacterium striatum blood isolates.
  • To emphasize the need for vigilance regarding multidrug resistance in this species.
  • To characterize the antibiotic susceptibility profile of a specific C. striatum blood isolate (DSM 45711).

Main Methods:

  • Blood culture isolation and identification of Corynebacterium striatum.
  • Antimicrobial susceptibility testing using disc diffusion methods.
  • Phenotypic characterization of antibiotic resistance patterns.

Main Results:

  • The study details the characteristics of a Corynebacterium striatum blood isolate (DSM 45711).
  • Clear antibiotic resistances were observed, indicating potential challenges in treatment.
  • The findings underscore the importance of reporting significant resistance patterns.

Conclusions:

  • Corynebacterium striatum should not be automatically dismissed as a contaminant in blood cultures.
  • Robust surveillance of antimicrobial resistance in C. striatum is essential for patient care.
  • Further investigation into the antibiotic susceptibility of this species is warranted.