[Morphofunctional characteristics of the uterus in dystrophic changes and necrosis in leiomyoma]

Morphologic, histochemical and fluorescent microscopic studies of leiomyomas with necrosis and degenerative changes have been done in 100 patients. Morphologic and functional features of the endometrium and myometrium were examined at tumor-adjacent and remote sites. The study showed no relation between the ischemic changes of uterine leiomyomas and morphological/functional status of the myometrium and endometrium. In the presence of leiomyoma, the endometrium undergoes primarily histophysiological and aging-related changes. The study findings suggest that surgery for necrotic leiomyoma should be organ-sparing.