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Updated: May 14, 2026

A Protocol to Acquire the Degenerative Tenocyte from Humans
Published on: June 9, 2018
Lateral epicondylitis of the elbow.
Rick Tosti1, John Jennings, J Milo Sewards
1Department of Orthopaedic Surgery and Sports Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA. rtosti@temple.edu
Tennis elbow (lateral epicondylitis) is a common elbow condition caused by repetitive motions. Most cases resolve with non-surgical treatments like physical therapy, but some may need surgery.
Area of Science:
- Orthopedics
- Sports Medicine
- Musculoskeletal Disorders
Background:
- Lateral epicondylitis, commonly known as tennis elbow, is a prevalent degenerative condition affecting the extensor tendon origin at the lateral humeral epicondyle.
- It is frequently associated with repetitive occupational or athletic activities that involve wrist extension and supination.
- Key symptoms include lateral elbow pain, discomfort during wrist extension, and diminished grip strength.
Purpose of the Study:
- To provide a comprehensive overview of lateral epicondylitis.
- To emphasize the importance of accurate clinical diagnosis and differential diagnosis.
- To outline current nonoperative and operative management strategies.
Main Methods:
- Clinical diagnosis based on patient history and physical examination.
- Evaluation of differential diagnoses to guide appropriate management.
- Review of nonoperative treatments (activity modification, physical therapy, injections) and surgical interventions.
Main Results:
- The majority of patients experience symptom improvement with nonoperative management.
- A small subset of patients may require surgical intervention for persistent symptoms.
- Surgical release of the extensor carpi radialis brevis tendon can be performed through various approaches.
Conclusions:
- Lateral epicondylitis is primarily diagnosed clinically.
- Nonoperative treatments are effective for most patients with tennis elbow.
- Surgical options exist for refractory cases, including percutaneous, arthroscopic, and open release procedures.
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