Glycosyl hydroperoxides
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Updated: May 14, 2026

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Barbara Szechner1, Bartłomiej Furman, Marek Chmielewski
1Institute of Organic Chemistry of the Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Abstract:
Synthesis of glycosyl hydroperoxides derived from 2,3,4,6-tetra-O-benzyl-d-glucopyranose and 2,3,4,6-di-O-isopropylidene-d-mannofuranose was performed via a Schmidt's imidate intermediate with hydrogen peroxide in an ethyl ether solution in the presence of an acid catalyst. Separation of the α- and β-anomers of the glycosyl hydroperoxides was achieved by chromatography.
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