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PORP vs. TORP: a meta-analysis.

Huiqian Yu1, Yingzi He, Yusu Ni

  • 1Department of Otorhinolaryngology, Shanghai Eye and ENT Hospital, Shanghai Medical College, Fudan University, 200031, Shanghai, China.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|February 13, 2013
PubMed
Summary
This summary is machine-generated.

Partial ossicular replacement prosthesis (PORP) demonstrated higher effectiveness than total ossicular replacement prosthesis (TORP) in ossicular chain reconstruction. PORP also showed superior long-term stability, though effectiveness varied in specific surgical subgroups.

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Area of Science:

  • Otolaryngology
  • Surgical Innovation
  • Biomaterials in Medicine

Background:

  • Ossicular chain reconstruction is a common surgical procedure to restore hearing.
  • Partial ossicular replacement prosthesis (PORP) and total ossicular replacement prosthesis (TORP) are widely used prostheses.
  • Comparative data on the long-term effectiveness and stability of PORP versus TORP is crucial for surgical decision-making.

Purpose of the Study:

  • To systematically compare and evaluate the effectiveness and stability of PORP versus TORP in ossicular chain reconstruction.
  • To identify potential differences in outcomes based on surgical subgroups.
  • To provide evidence-based insights for surgeons selecting prostheses.

Main Methods:

  • A comprehensive meta-analysis was conducted.
  • Included 40 eligible investigations involving 4,311 subjects.
  • Compared outcomes of PORP and TORP regarding effectiveness and prosthesis stability.

Main Results:

  • PORP showed significantly higher effectiveness than TORP (RR = 1.28, p < 0.00001).
  • No significant difference in effectiveness was found in staged procedures or cholesteatoma subgroups.
  • PORP demonstrated significantly superior long-term stability compared to TORP (RR = 0.37, p = 0.02).

Conclusions:

  • PORP is generally more effective and stable than TORP for ossicular chain reconstruction.
  • Effectiveness differences were not significant in specific subgroups like staged procedures or cholesteatoma cases.
  • The findings support PORP as a favorable option, particularly for long-term stability.