Associations between obesity and inflammatory sinonasal disorders
1Division of Otolaryngology, Brigham and Women's Hospital and Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02115, USA. neiloy@massmed.org
The Laryngoscope
|February 13, 2013
Summary
Adult obesity is linked to higher rates of allergic rhinitis (AR) and chronic rhinosinusitis (CRS). This study found increased odds of both conditions in obese individuals, highlighting a significant association.
Area of Science:
- Otolaryngology
- Public Health
- Epidemiology
Background:
- Obesity is a growing public health concern with numerous associated comorbidities.
- Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are common conditions affecting the upper airway.
- The relationship between adult obesity and the prevalence of CRS and AR requires further investigation.
Purpose of the Study:
- To determine the association between adult obesity and the prevalence of chronic rhinosinusitis (CRS).
- To investigate the association between adult obesity and the prevalence of allergic rhinitis (AR).
Main Methods:
- Cross-sectional analysis utilizing data from the U.S. Medical Expenditure Panel Survey (2008-2010).
- Identification of adult cases of CRS and AR based on survey responses.
- Statistical adjustment for demographic factors, insurance, and comorbidities to calculate odds ratios for CRS/AR in obese individuals (BMI ≥ 30 kg/m²).
Main Results:
- Over 17.6 million adults reported AR and 13.0 million reported CRS.
- Approximately 29% of adults (64.9 million) were classified as obese.
- Obesity was significantly associated with increased odds of AR (OR=1.22) and CRS (OR=1.31).
- Increasing BMI as a continuous variable also showed a significant association with both AR and CRS.
Conclusions:
- Adult obesity is demonstrably associated with a higher prevalence of both allergic rhinitis and chronic rhinosinusitis.
- These findings suggest obesity as a potential risk factor or contributing element in the development or exacerbation of AR and CRS.
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