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Related Concept Videos

Chambers of the Heart01:16

Chambers of the Heart

The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Development of the Heart01:27

Development of the Heart

The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...

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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Published on: October 28, 2020

Double outlet right ventricle versus aortic dextroposition: morphologically distinct defects.

Angelo Restivo1, Marta Unolt, Carolina Putotto

  • 1Department of Pediatrics, Pediatric Cardiology, University of Rome La Sapienza, Rome, Italy.

Anatomical Record (Hoboken, N.J. : 2007)
|February 13, 2013
PubMed
Summary

Double outlet right ventricle (DORV) and aortic dextroposition (AD) are distinct congenital heart defects. Morphological differences, including septal insertion and great artery arrangement, differentiate these conditions, aiding in accurate clinical diagnosis.

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Area of Science:

  • Cardiovascular Morphology
  • Congenital Heart Disease Research
  • Pediatric Cardiology

Background:

  • Double outlet right ventricle (DORV) and aortic dextroposition (AD) share similarities in ventriculo-arterial connections.
  • Accurate differentiation between DORV and AD is crucial for effective clinical diagnosis and management.

Purpose of the Study:

  • To delineate the distinct morphological features differentiating DORV from AD.
  • To identify key anatomical landmarks that distinguish these congenital heart defects.

Main Methods:

  • Comparative morphological analysis of DORV and AD cases.
  • Detailed examination of septal insertion patterns and great artery arrangements.

Main Results:

  • A specific infundibular septum insertion into the septomarginal trabeculation characterizes AD, absent in DORV.
  • Spiraliform versus straight parallel arrangement of great arteries serves as a distinguishing feature.
  • Association of straight parallel great arteries with DORV and transposition of the great arteries in asplenia heterotaxy defects was noted.

Conclusions:

  • DORV and AD represent distinct morphological entities, not to be collectively grouped in clinico-pathological diagnoses.
  • Morphological differentiation based on septal insertion and great artery arrangement is vital.
  • Findings support the exclusion of subaortic ventricular septal defects and spiraliform great arteries in the asplenia group of heterotaxy anomalies.