Neglected papillary thyroid carcinoma seven years after initial diagnosis

Area of Science:

• Oncology
• Endocrinology
• Pathology

Background:

• Papillary thyroid carcinoma (PTC) is the most prevalent epithelial thyroid tumor, comprising over 80% of cases.
• Advances in ultrasonography and fine-needle aspiration biopsy have improved early detection.
• Exceptionally large PTCs can develop due to recurrent disease or patient neglect.

Purpose of the Study:

• To report an extremely rare case of a giant, neglected papillary thyroid carcinoma.
• To illustrate the potential complications and clinical presentation of such rare cases.

Main Methods:

• Case report of a 72-year-old woman with a neglected giant exophytic papillary thyroid carcinoma.
• Diagnostic imaging via computed tomography (CT) to assess tumor size and extent.
• Management focused on controlling hemorrhage.

Main Results:

• The patient presented with a giant exophytic papillary thyroid carcinoma measuring 17 × 12 cm.
• The tumor caused significant tracheal displacement and extended into the mediastinum.
• Hemorrhage was managed, and the patient was discharged.

Conclusions:

• Giant papillary thyroid carcinomas are exceptionally rare but can lead to severe complications.
• Patient awareness and adherence to treatment are crucial for managing thyroid malignancies.
• This case underscores the importance of prompt medical attention for thyroid nodules.