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Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
12:24

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes

Published on: June 3, 2014

Von Willebrand factor containing factor VIII concentrates

E Berntorp1

  • 1Department for Coagulation Disorders, University of Lund, University Hospital, Malmö, Sweden. erik.berntorp@medforsk.mas.lu.se

Haemophilia : the Official Journal of the World Federation of Hemophilia
|February 13, 2013
PubMed

There are several plasma derived von Willebrand factors (vWF) containing factor (FVIII) concentrates that can be used in the treatment of von Willebrand disease (vWD). All concentrates are effective in attaining normal postinfusion levels or of FVIII:C but it is difficult to achieve normalization of the bleeding time even with concentrates containing almost all vWF multimers including those of high molecular weight. Haemate P (Centeon) may be considered as the golden standard concentrate available at present. However, the development of more purified vWF concentrates devoid of FVIII:C is the goal for future development.

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