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Updated: May 14, 2026

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
Published on: June 25, 2013
[Possible clinical potential in reverting muscular block with sugammadex in anaesthesia and surgery]
Emilie Øberg1, Casper Claudius
1Anæstesiologisk Afdeling, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark. emilieberthelsen@hotmail.com
Abstract:
Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to post-operative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to the NMB rocuronium - which within 1-3 minutes neutralizes the effects of rocuronium. High-dose rocuronium is now an alternative to suxamethonium in acute or short procedures and in a situation, where ventilation/intubating cannot be performed, sugammadex can reverse the rocuronium blockade within minutes.
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