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Bioactivity evaluation of three calcium silicate-based endodontic materials
1Division of Cariology, Operative Dentistry and Endodontics, Department of Oral Health Science, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan. han@dent.niigata-u.ac.jp
International Endodontic Journal
|February 14, 2013
Summary
EndoSequence BC sealer demonstrated less calcium ion release and shallower calcium and silicon incorporation into root dentine compared to white ProRoot MTA and Biodentine over 90 days.
Area of Science:
- Biomaterials Science
- Dental Materials Science
- Mineral Trioxide Aggregate Research
Background:
- Calcium silicate-based sealers are crucial for root canal therapy.
- Understanding their interaction with dentine is vital for treatment success.
- Apatite formation and ion incorporation influence sealer efficacy.
Purpose of the Study:
- To compare apatite formation and calcium (Ca) and silicon (Si) incorporation into dentine by white ProRoot MTA (WMTA), EndoSequence BC sealer (BC sealer), and Biodentine.
- To evaluate the influence of phosphate-buffered saline (PBS) immersion on these properties.
Main Methods:
- Human root sections were filled with WMTA, BC sealer, or Biodentine.
- Samples were immersed in PBS for up to 90 days.
- Surface precipitates and interfacial dentine were analyzed for morphology and elemental composition using electron probe microanalysis; Ca ion release was quantified.
Main Results:
- All materials formed apatite precipitates with a Ca/P ratio of 1.6:2.0.
- Intratubular tag-like structures were observed.
- Ca and Si incorporation depths followed the order: Biodentine > WMTA > BC sealer.
- Ca ion release followed the order: Biodentine > WMTA > BC sealer.
Conclusions:
- BC sealer exhibited significantly less Ca ion release compared to WMTA and Biodentine.
- BC sealer showed reduced Ca and Si incorporation into dentine over 90 days.
- Biodentine and WMTA demonstrated superior dentine interaction and ion release profiles.