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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Patient-prosthesis mismatch in patients with aortic valve replacement
Yuichiro Kaminishi1, Yoshio Misawa, Junjiro Kobayashi
1Division of Cardiovascular Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan. tcvkamyu@jichi.ac.jp
General Thoracic and Cardiovascular Surgery
|February 14, 2013
Summary
Patient-prosthesis mismatch (PPM) after aortic valve replacement (AVR) was linked to patient factors like age and comorbidities, but not short-term mortality. Understanding these risk factors is key for optimizing AVR outcomes.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Clinical Outcomes Research
Background:
- Patient-prosthesis mismatch (PPM) is a potential concern following aortic valve replacement (AVR).
- The impact of PPM on clinical outcomes in isolated AVR patients requires further investigation.
Purpose of the Study:
- To retrospectively examine the prevalence and risk factors of PPM in patients undergoing isolated AVR.
- To assess the association between PPM and short-term clinical outcomes.
Main Methods:
- Analysis of isolated AVR cases from the Japan Adult Cardiovascular Surgery Database (JACVSD) between 2008-2009.
- Definition of PPM as an effective orifice area index ≤ 0.85 m²/cm².
- Comparison of demographic and clinical characteristics between PPM and non-PPM groups.
Main Results:
- PPM was identified in 8.5% of 3,609 analyzed cases.
- PPM patients were older, had higher BMI, and more comorbidities including diabetes, dyslipidemia, hypertension, and coronary artery disease.
- Increased perioperative blood transfusion, dialysis, postoperative ventilation, and ICU stay were observed in the PPM group.
Conclusions:
- Key risk factors for PPM include age, aortic valve stenosis, dyslipidemia, hypertension, prior myocardial infarction, percutaneous coronary intervention, diabetes, cerebrovascular disease, and high BMI.
- PPM was not found to be an independent risk factor for short-term mortality in this cohort.
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