del(2)(p23): a new recurrent abnormality in acute myeloid leukemia
V Najfeld1, A Scalise, S Fruchtman
1Tumor Cytogenetics Laboratory, Polly Annenberg Levee Hematology Center, Mount Sinai Medical Center, New York, New York 10029.
Cancer Genetics and Cytogenetics
|June 1, 1990
Abstract:
In two patients with acute myeloid leukemia, we found a new chromosome abnormality: del(2)(p23) which was detected in 13% and 50% of studied bone marrow cells, respectively. In patient one, del(2p) was an additional abnormality to t(8;21), while patient two had del(2p) as the sole abnormality. Based on our observation and a review of the literature we propose that del(2p) is a new recurrent chromosome abnormality for acute myeloid leukemia.
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