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Choroid plexus papillomas in infancy and childhood
A Spallone1, F S Pastore, R Giuffre
1Division of Neurosurgery, 2nd University of Rome Tor Vergata, Italy.
Summary
Choroid plexus papilloma is rare in children, often presenting with increased intracranial pressure. Surgical management is typically successful, emphasizing meticulous technique to prevent tumor seeding.
Area of Science:
- Pediatric Neurosurgery
- Pediatric Oncology
- Neuropathology
Background:
- Choroid plexus papillomas (CPPs) are uncommon pediatric brain tumors.
- These tumors account for a small fraction of childhood intracranial neoplasms.
- Symptoms often relate to increased intracranial pressure.
Purpose of the Study:
- To review clinical features, diagnosis, and management of pediatric choroid plexus papilloma.
- To evaluate surgical outcomes and identify factors influencing prognosis.
- To highlight the importance of surgical technique in managing these tumors.
Main Methods:
- Retrospective analysis of 15 pediatric cases of choroid plexus papilloma.
- Review of clinical presentation, radiological findings, pathological data, and surgical outcomes.
- Correlation of treatment approach with patient results.
Main Results:
- Choroid plexus papilloma represented approximately 3% of pediatric brain tumors in the study cohort.
- Most cases presented with signs of increased intracranial pressure.
- Radical surgical resection was achievable in most non-malignant cases, leading to satisfactory outcomes.
- Malignant variants posed challenges to complete surgical removal.
- Meticulous surgical technique was crucial for preventing intraoperative tumor seeding.
Conclusions:
- Choroid plexus papilloma is a manageable pediatric brain tumor with generally favorable outcomes.
- Surgical intervention is the primary treatment modality.
- Careful surgical planning and execution are essential to optimize results and minimize complications such as tumor seeding.