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Updated: May 14, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
[Effects of molybdenum and hypoxia on the cardiovascular system of experimental animals]
Abstract:
The investigation had the purpose to study an impact of environmental pollution by molybdenum-containing wastes, and Mo dose-dependent effect on the cardiac structure and function in hypoxic conditions. The experiments were performed with white Wistar rats using electrophysiological and histological investigations, radioimmunoassay, immune-enzyme assay, polarographic and mathematical methods. It was shown that the dose Mo of 0.0125 mg/kg of body mass stimulates and raises the ceiling of the normal heart function (NHFC) by 1.2 km. The toxic dose of 1.25 mg/kg breaks the structure, impairs myocardial performance and reduces NHFC by one half; also, it causes gross disorders in protein metabolism and brings about irreversible structural changes in the myocardium.
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