Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
An Overview of Psychoactive Drugs01:28

An Overview of Psychoactive Drugs

Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Twinning as a risk factor for neonatal acute intestinal diseases: a case-control study.

Frontiers in pediatrics·2024
Same author

Anti-SARS-CoV-2 antibody levels and kinetics of vaccine response: potential role for unresolved inflammation following recovery from SARS-CoV-2 infection.

Scientific reports·2022
Same author

Hospital workers mental health during the COVID-19 pandemic: methods of data collection and characteristics of study sample in a university hospital in Milan (Italy).

BMC medical research methodology·2021
Same author

Characteristics of 1573 healthcare workers who underwent nasopharyngeal swab testing for SARS-CoV-2 in Milan, Lombardy, Italy.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2020
Same author

Prevalence of abdominal aortic aneurysms and its relation with cardiovascular risk stratification: protocol of the Risk of Cardiovascular diseases and abdominal aortic Aneurysm in Varese (RoCAV) population based study.

BMC cardiovascular disorders·2016
Same author

Workplace drug testing on urine samples: evidence for improving efficacy of a first-level screening programme.

La Medicina del lavoro·2015
Same journal

Background Music in elderly nursing home: a feasibility explorative study.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Needle stick injuries among nurses in Italy: a review.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Self-compassion and secondary traumatization: results of an observational study carried out in Covid hospital ordinary units].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Remote functional evaluation after reconstruction of the anterior cruciate ligament in amateur sportsmen with sedentary work].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Communicating bad news: attitudes and modes of communication of the health professions.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Mortality study in a cohort of entertainment workers].

Giornale italiano di medicina del lavoro ed ergonomia·2023
See all related articles

Related Experiment Video

Updated: May 14, 2026

Driving Under the Influence: How Music Listening Affects Driving Behaviors
07:25

Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

[Psychotropic substances and driving].

L Bordini1, L Riboldi, M M Ferrario

  • 1U.O. Medicina del Lavoro 1, "Clinica del Lavoro L. Devoto", Fondazione IRCCS CA' GRANDA Ospedale Maggiore Policlinico-Milano. lorenzo.bordini@policlinico.mi.it

Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia
|February 15, 2013
PubMed
Summary
This summary is machine-generated.

Consuming alcohol, drugs, or medication significantly impairs driving ability, increasing accident risks for professional drivers. More research is needed to fully understand this link and inform prevention strategies.

More Related Videos

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
07:02

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

Published on: February 11, 2019

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Driving Under the Influence: How Music Listening Affects Driving Behaviors
07:25

Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
07:02

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

Published on: February 11, 2019

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Area of Science:

  • Occupational Health
  • Forensic Toxicology
  • Road Safety Research

Context:

  • Driving is a complex activity significantly impacted by psychotropic substance use.
  • Occupational physicians encounter this issue frequently due to the large number of professional drivers.
  • The social relevance is high due to potential involvement and severe outcomes.

Purpose:

  • To explore the association between psychotropic substance consumption and increased risk of work-related accidents/injuries.
  • To highlight the need for better definition and understanding of the impact of psychoactive substances on driving.
  • To emphasize the crucial role of occupational physicians in prevention, clinical management, and rehabilitation.

Summary:

  • Psychotropic substance use (alcohol, drugs, medication) demonstrably affects complex performance tasks like driving.
  • Existing studies on the link between substance use and occupational accidents show inconsistent results.
  • Further research is essential to clarify the risks associated with psychoactive substance consumption while driving.

Impact:

  • Informs occupational health policies and practices regarding substance use and driving.
  • Provides a basis for improving prevention, clinical assessment, and rehabilitation programs for professional drivers.
  • Contributes to enhancing road safety and reducing work-related injuries and fatalities.