Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Concentrations: Measurements01:23

Drug Concentrations: Measurements

Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma —...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and clinical impact of incidental findings on the unenhanced CT images of PET/CT scan in patients with multiple myeloma: the value of radiological reporting in the multimodal hybrid imaging.

European review for medical and pharmacological sciences·2022
Same author

Sentinel node biopsy in thin melanoma: a retrospective descriptive cohort study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Can harmful lifestyle, obesity and weight changes increase the risk of breast cancer in BRCA 1 and BRCA 2 mutation carriers? A Mini review.

Hereditary cancer in clinical practice·2021
Same author

Endocannabinoid system expression in ovarian epithelial tumors according to the dualistic model of ovarian carcinogenesis.

European review for medical and pharmacological sciences·2021
Same author

Prophylactic sublay non-absorbable mesh positioning following midline laparotomy in a clean-contaminated field: randomized clinical trial (PROMETHEUS).

The British journal of surgery·2021
Same author

Body Composition Change, Unhealthy Lifestyles and Steroid Treatment as Predictor of Metabolic Risk in Non-Hodgkin's Lymphoma Survivors.

Journal of personalized medicine·2021
Same journal

Background Music in elderly nursing home: a feasibility explorative study.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Needle stick injuries among nurses in Italy: a review.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Self-compassion and secondary traumatization: results of an observational study carried out in Covid hospital ordinary units].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Remote functional evaluation after reconstruction of the anterior cruciate ligament in amateur sportsmen with sedentary work].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Communicating bad news: attitudes and modes of communication of the health professions.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Mortality study in a cohort of entertainment workers].

Giornale italiano di medicina del lavoro ed ergonomia·2023
See all related articles

Related Experiment Video

Updated: May 14, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

[Reference values for 42 trace elements in biological fluids (database RE-VA)].

C Minoia1, A Ronchi, J Businaro

  • 1Laboratorio di Misure Ambientali e Tossicologiche, Fondazione S. Maugeri, Istituto Scientifico di Pavia, Italy. claudio.minoia@fsm.it

Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia
|February 15, 2013
PubMed
Summary
This summary is machine-generated.

This study establishes reference values for 42 trace elements in human biological samples using advanced ICP-MS techniques. Findings highlight analytical sensitivities and potential environmental influences on element levels.

More Related Videos

Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure
08:40

Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure

Published on: March 21, 2017

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

Related Experiment Videos

Last Updated: May 14, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure
08:40

Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement Procedure

Published on: March 21, 2017

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

Area of Science:

  • Analytical Chemistry
  • Environmental Science
  • Biochemistry

Context:

  • Advancements in multi-elementary techniques like inductively coupled plasma mass spectrometry (ICP-MS) simplify trace element determination in biological matrices.
  • Accurate interference control, especially polyatomic, is crucial, necessitating high-resolution ICP-MS, ICP-OES, and ETA-AAS.

Purpose:

  • To establish reference values for 42 elements in serum, plasma, whole blood, and urine.
  • To investigate physiological variables, life habits, and food intake in relation to element levels.
  • To identify analytical and pre-analytical factors causing inconsistencies in trace element determination.

Summary:

  • The RE-VA study analyzed 162 subjects, providing reference values for 42 elements using ICP-MS techniques, including dynamic reaction cell (DRC-ICP-MS).
  • Significant differences were observed for elements like W, Ba, Cs, and Pt compared to other studies, attributed to the high sensitivity of DRC-ICP-MS.
  • Comparative studies with Sector Field ICP-MS confirmed matching values, underscoring the analytical precision.

Impact:

  • Provides crucial reference data for trace element analysis in human biological samples.
  • Highlights the need to consider environmental factors (industrial areas, landfills) in population studies.
  • Aims to expand the study across Europe to create a comprehensive elemental database.