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Updated: May 14, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
Published on: May 29, 2019
[Meta analysis indices of genotoxic damage in urban pollution exposed workers]
A Sancini1, F Tomei, A Capozzella
1Dipartimento di Anatomia, Istologia, Medicina Legale e Ortopedia, Scuola di Specializzazione in Medicina del Lavoro, "Sapienza" Università di Roma, Italy.
Objectives:
The aim of this study is to examine if urban pollution can modify indices of genotoxic damage.
Methods:
Research of articles inherent in the evaluation of these alterations. Differents categories of exposed workers are included in the study (cases, in number of 7287) and compaired with no exposed workers (controls, in number of 8054). To calculate the result of meta-analysis the Effect Size (ES) was used and the confidence interval was calculated.
Results:
In this category we evaluated 54 studies and we observed significantly differences in the complex.
Conclusions:
Starting from the individual variables analysis investigated, between exposed and not exposed group, we underline the utility to deepen the studies concerning of these parameters, to appreciate their benefits and to safeguard health of exposed workers.
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