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Updated: May 14, 2026

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies

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Published on: August 20, 2021

Complete genome sequence of Pyrobaculum oguniense.

David L Bernick¹, Kevin Karplus, Lauren M Lui

¹Biomolecular Engineering, University of California., Santa Cruz, California, USA.

Standards in Genomic Sciences

|February 15, 2013

Summary

This summary is machine-generated.

We sequenced the genome of Pyrobaculum oguniense TE7, a hyperthermophilic archaeon. Surprisingly, it shares high similarity with a distant anaerobic relative, suggesting conserved genome dynamics in this genus.

Keywords:

Crenarchaea Pyrobaculum arsenaticum Pyrobaculum oguniense inversion

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Area of Science:

Microbiology
Genomics
Archaea

Background:

Pyrobaculum oguniense TE7 is an aerobic hyperthermophilic archaeon.
It was isolated from a hot spring in Japan.

Purpose of the Study:

To describe the genome of Pyrobaculum oguniense TE7.
To compare its genome with its closest known relative, Pyrobaculum arsenaticum.

Main Methods:

Genome sequencing and annotation.
Comparative genomic analysis.

Main Results:

The genome consists of a 2,436,033 bp chromosome and a 16,887 bp extra-chromosomal element.
2,800 protein-coding genes and 145 RNA genes were annotated.
High synteny and nucleotide identity were found between P. oguniense and P. arsenaticum, despite geographical and metabolic differences.

Conclusions:

The genome of P. oguniense TE7 provides insights into the genetic makeup of hyperthermophilic archaea.
The unexpected genomic similarity suggests conserved genome dynamics within the Pyrobaculum genus.
Deep sequencing revealed potential genome dynamics shared across species.