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Updated: May 14, 2026

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
Asymptomatic urethritis is common and is associated with characteristics that suggest sexually transmitted etiology
Catherine W Gillespie1, Lisa E Manhart, M Sylvan Lowens
1Children's Research Institute, Children's National Medical Center, Washington, DC, USA. cgillesp@childrensnational.org
Abstract:
We evaluated 236 asymptomatic men for urethritis, assessed sexual behaviors, and tested urine for pathogens. Asymptomatic urethritis was present in 38 (16.1%). Of these, nearly half (42.1%) had a previously unrecognized discharge on examination; only 18.4% had a known pathogen. Correlates included black race, anal intercourse, and number of sex partners.
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