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Related Concept Videos

Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

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Related Experiment Video

Updated: May 14, 2026

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
07:47

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Published on: September 15, 2023

Nutrigenomics and cancer.

Ali M Ardekani1, Sepideh Jabbari

  • 1Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Avicenna Journal of Medical Biotechnology
|February 15, 2013
PubMed
Summary

Dietary habits can help prevent cancer. Nutrigenomics studies how genes and diet interact, enabling personalized nutrition strategies to reduce cancer risk by understanding individual genetic variations and nutrient responses.

Keywords:
Bioactive food componentsBiomarkerCancer preventionNutrigeneticsNutrigenomics

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Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
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Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
07:48

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

Published on: December 26, 2016

Area of Science:

  • Nutritional Science
  • Genetics
  • Cancer Prevention

Background:

  • Cancer incidence is rising, necessitating effective preventive strategies.
  • Dietary modifications represent a promising approach for cancer risk reduction.
  • Understanding individual responses to bioactive food components is crucial for personalized interventions.

Purpose of the Study:

  • To explore the role of nutrigenomics in understanding gene-diet interactions for cancer prevention.
  • To highlight the importance of individual susceptibility in dietary interventions.
  • To identify key molecular targets for cancer prevention through personalized nutrition.

Main Methods:

  • Investigating the biological effects of food components on cancer.
  • Assessing individual susceptibility based on nutrient-nutrient interactions and genetics.
  • Utilizing nutrigenomic approaches to study nutrient-gene expression interactions.

Main Results:

  • Nutrients can influence gene expression and induce changes in DNA and proteins.
  • Individual responses to bioactive food components vary due to genetic factors and target tissues.
  • Nutrigenomics offers insights into how nutrition affects gene variations and epigenetic events.

Conclusions:

  • Personalized nutrition strategies based on nutrigenomics can enhance cancer prevention.
  • Identifying gene-diet interaction components can lead to targeted cancer prevention therapies.
  • Further research in nutrigenomics is essential for developing effective dietary interventions against cancer.