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A comparison between brachial and echocardiographic systolic time intervals
Ho-Ming Su1, Tsung-Hsien Lin, Po-Chao Hsu
1Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Plos One
|February 15, 2013
Summary
Systolic time intervals (STIs) measured by an ankle-brachial index device closely correlate with echocardiography results. These brachial STIs effectively predict reduced left ventricular ejection fraction, aiding cardiac function assessment.
Area of Science:
- Cardiology
- Biomedical Engineering
- Diagnostic Imaging
Background:
- Systolic time intervals (STIs) are noninvasive measures of cardiac function.
- Echocardiography is a standard method for STI assessment.
- Ankle-brachial index (ABI)-form devices offer automated brachial STI measurements.
Purpose of the Study:
- To evaluate if brachial STIs from an ABI-form device correlate with echocardiographic STIs.
- To compare the diagnostic accuracy of brachial and echocardiographic STIs for predicting left ventricular ejection fraction (LVEF) <50%.
Main Methods:
- 849 patients were included in the study.
- Brachial STIs (bPEP, bET) were measured using an ABI-form device.
- Echocardiographic STIs (PEP, ET) were measured.
- Agreement assessed via correlation and Bland-Altman plots.
Main Results:
- Significant correlations were found between brachial and echocardiographic STIs (r=0.644 for bPEP/PEP, r=0.850 for bET/ET, r=0.708 for bPEP/bET and PEP/ET).
- Areas under the curve for predicting LVEF <50% were 0.771 for brachial STIs and 0.765 for echocardiographic STIs.
- Brachial STIs demonstrated good agreement and diagnostic value compared to echocardiographic STIs.
Conclusions:
- Brachial STIs from ABI-form devices are reliable alternatives to echocardiographic STIs.
- Automated brachial STIs can aid in evaluating left ventricular systolic dysfunction and predicting reduced LVEF.
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