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Updated: May 14, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
Emerging role of colloidal drug delivery systems (CDDS) in NSAID topical administration
Carmelo Puglia1, Giorgia Giusy Tirendi, Francesco Bonina
1Department of Drug Sciences, University of Catania, Viale Andrea Doria n°6 95125 Catania, Italy. capuglia@unict.it
Abstract:
NSAIDs are the most commonly prescribed category of drugs for the treatment of musculoskeletal pain and inflammation associated with many conditions. Topical administration of these drugs is always the best choice since adverse effects occur commonly with systemic NSAID therapy. Colloidal drug delivery systems (CDDS) are interesting systems, which are able to improve the duration of drug residence in the skin and to allow an achievable drug sustained and controlled release compared to conventional topical formulations. This review focuses on micro and nanoemulsions, vesicular carriers and nanoparticles as novel high efficiency delivery systems of NSAIDs in topical applications.
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