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Updated: May 14, 2026

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis
Published on: July 31, 2010
Folding and association of a homotetrameric protein complex in an all-atom Go model
W M Berhanu1, P Jiang, U H E Hansmann
1Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019-5251, USA.
Abstract:
The 84-residue homotetrameric BBAT1 is one of the smallest stable protein complexes and therefore is a good test system to study the self-assembly of multimeric proteins. We have researched for this protein the interplay between the folding of monomers and their assembly into tetramers. Replica exchange molecular dynamics simulations relying on a Go model are compared with earlier simulations that use the physics-based coarse-grained UNRES model.
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