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Biofunctionalized silver nanoparticles: advances and prospects.
Aswathy Ravindran1, Preethy Chandran, S Sudheer Khan
1Center for Nanotechnology and Advanced Biomaterials (CeNTAB), School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamilnadu, India. aswathy85@gmail.com
Colloids and Surfaces. B, Biointerfaces
|February 16, 2013
Summary
Silver nanoparticles offer unique biomedical potential but face toxicity and aggregation issues. Biofunctionalization enhances their biocompatibility and expands applications in nanotechnology.
Area of Science:
- Nanotechnology
- Biomedical Engineering
- Materials Science
Background:
- Nanoscale materials exhibit unique size-dependent properties, driving nanotechnology's promise in biomedical fields.
- Silver nanoparticles (AgNPs) are of significant interest due to their optical, electrical, and antimicrobial properties.
- Toxicity and aggregation of AgNPs limit their optimized biomedical applications.
Purpose of the Study:
- To review the application domains of silver nanoparticles in biomedicine.
- To provide an overview of current strategies for biofunctionalizing AgNPs.
- To highlight the applications of functionalized AgNPs.
Main Methods:
- Review of existing literature on silver nanoparticle applications.
- Analysis of biofunctionalization techniques for surface modification of AgNPs.
- Categorization of applications based on functionalized AgNP properties.
Main Results:
- Silver nanoparticles possess diverse biomedical applications.
- Biofunctionalization strategies improve AgNP biocompatibility and biological applicability.
- Surface modification overcomes limitations of bare AgNPs, enabling tailored uses.
Conclusions:
- Rational selection of biomolecules for AgNP functionalization is crucial.
- Biofunctionalized AgNPs offer enhanced biocompatibility and expanded therapeutic potential.
- This review consolidates knowledge on AgNP applications and functionalization strategies.
