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Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery
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Hold the heparin.

Nicholas Wettersten1, Ezra Amsterdam

  • 1Department of Internal Medicine, University of California (Davis) Medical Center, Sacramento, CA 95817, USA.

Critical Pathways in Cardiology
|February 16, 2013
PubMed
Summary
This summary is machine-generated.

Dynamic T-wave inversions on ECGs can mimic heart attacks but are nonspecific. This case highlights that intracranial bleeds, not just acute coronary syndrome, can cause these findings and elevated troponin.

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Area of Science:

  • Cardiology
  • Neurology
  • Emergency Medicine

Background:

  • Dynamic electrocardiographic T-wave inversions are often concerning for myocardial ischemia or infarction.
  • However, these ECG findings are nonspecific and can be associated with various conditions.

Observation:

  • A young man presented with headache and dizziness, exhibiting marked hypertension, deepening T-wave inversions, and elevated troponin.
  • Initial assessment raised concerns for acute coronary syndrome (ACS).

Findings:

  • Further evaluation revealed intraventricular hemorrhage on noncontrast computed tomography of the head.
  • This indicated that the ECG changes and troponin elevation were secondary to the intracranial bleed.

Implications:

  • T-wave inversions and troponin elevation in the context of intracranial hemorrhage are well-described phenomena.
  • It is crucial to consider a broad differential diagnosis, including intracranial bleeds, before initiating ACS treatment to prevent adverse outcomes.